Sahlhealth
Sahlhealth
sahllogo

X Linked Agammaglobulinemia

X-linked agammaglobulinemia (a-gam-uh-glob-u-lih-NEE-me-uh) — or XLA — is an inherited (genetic) immune system disorder that reduces your ability to fight infections. People with XLA may experience infections of the inner ear, sinuses, respiratory tract, bloodstream and internal organs.

XLA affects males almost exclusively, although females can be genetic carriers of the condition. Most people with XLA are diagnosed in infancy or early childhood, once it's clear that they are experiencing repeated infections. Sometimes, people are not diagnosed until adulthood.

Similar Diseases

  • Acute inflammatory demyelinating polyneuropathy

    Guillain-Barre (gee-YAH-buh-RAY) syndrome is a rare disorder in which your body’s immune system attacks your nerves. Weakness and tingling in your extremities are usually the first symptoms. These sensations can quickly spread, eventually paralyzing your whole body. In its most severe form Guillain-Barre syndrome is a medical emergency. Most people with the condition must be […]

  • Acute febrile neutrophilic dermatosis

    Sweet’s syndrome is a rare skin condition. Its main signs include fever and painful skin lesions that appear mostly on your arms, neck, head and trunk. The exact cause of Sweet’s syndrome isn’t known. In some people, it’s triggered by an infection, illness or certain medications. Sweet’s syndrome can also occur with some types of […]

  • Acute coronary syndrome

    Acute coronary syndrome is a term used to describe a range of conditions associated with sudden, reduced blood flow to the heart. One condition under the umbrella of acute coronary syndrome is myocardial infarction (heart attack) — when cell death results in damaged or destroyed heart tissue. Even when acute coronary syndrome causes no cell […]

  • Actinic keratosis

    An actinic keratosis (ak-TIN-ik ker-uh-TOE-sis) is a rough, scaly patch on your skin that develops from years of exposure to the sun. It’s most commonly found on your face, lips, ears, back of your hands, forearms, scalp or neck. Also known as a solar keratosis, an actinic keratosis enlarges slowly and usually causes no signs […]

  • Acromegaly

    Acromegaly is a hormonal disorder that develops when your pituitary gland produces too much growth hormone during adulthood. When this happens, your bones increase in size, including those of your hands, feet and face. Acromegaly usually affects middle-aged adults. In children who are still growing, too much growth hormone can cause a condition called gigantism. […]